Domesticating organ transplant

Domesticating home networks

This thesis addresses the following question: How should domestic networks be reinvented to support self-management by domestic users? It takes a user-centred design approach to redesign the underlying domestic network infrastructure to better fit domestic users. The overall aim of this work is to create user-centred mechanisms to support self-management of domestic networks by domestic users. ...

Tolerance in Solid-Organ Transplant.

Immunotolerance, which is nonimmunologic reactivity to specific tissue, was demonstrated in animals in the 1950s. However, despite assiduous efforts, it has not been reproduced in human solid-organ transplant to date. Fortuitously, clinical operational tolerance, which is stable graft function for > 1 year with no immunosuppression, has been demonstrated, primarily in a few nonadherent recipien...

Chimerism after Whole Organ Transplant.

Nocardiosis in Solid Organ Transplant

The genus Nocardia includes more than 80 known species, with at least 33 of them related to human pathology [2,3]. It is an opportunistic pathogen, causing infection generally in immunosuppressed, mainly with long exposure to corticosteroids, transplanted or HIV positive patients. It has worldwide distribution and is very ubiquitous, being found in terrestrial and aquatic environments as well a...

Arthroplasty in organ transplant patients

The number of solid organ transplants performed in the United States continues to increase annually as does survival after transplant. These unique patients are increasingly likely to present to arthroplasty surgeons for elective hip or knee replacement secondary to a vascular necrosis from chronic immunosuppression, or even age-related development of osteoarthritis. Transplant recipients have ...